Glycoursodeoxycholic acid

CAS No. 64480-66-6

Glycoursodeoxycholic acid ( Ursodeoxycholylglycine;GUDCA )

Catalog No. M19973 CAS No. 64480-66-6

Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Glycoursodeoxycholic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.
  • Description
    Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain and almost all bile acids in the bile duct therefore exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals.
  • Synonyms
    Ursodeoxycholylglycine;GUDCA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    64480-66-6
  • Formula Weight
    449.62
  • Molecular Formula
    C26H43NO5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mg/mL;Ethanol: 2 mg/mL
  • SMILES
    C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Goto T et al. LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):69-77.
molnova catalog
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